Gao L, Chen P, Feng J, Guo T, Zhang M, Ho TV, Chen JF, Chai Y. Temporally regulated FGFR2–retinoic acid signaling mediates dura mater–suture mesenchyme interactions to prevent craniosynostosis in mice. Int J Oral Sci. Accepted.
Category: Publications
New Publication in Nature Communications
Chen P, Meng L, Lan L, Feng J, Guo T, Gao L, Hekmat H, Ly C, Zhang M, Cha S, Ho TV, Chai Y. TGFβ-mediated dural progenitor cell migration into the coronal suture is crucial for preventing craniosynostosis. Nat Commun. 2026 May 19. doi: 10.1038/s41467-026-73292-w. Epub ahead of print. PMID: 42156771.
New Publication in Bone Research
Meng L, Zhang M, Feng J, Guo T, Hekmat H, Ziaei H, Chen P, Harouni A, Ho TV, Chai Y. KDM6B safeguards mineralized tissue homeostasis from mechanical stress through epigenetic control of PIEZO1-mediated mechanotransduction in the mouse incisor. Bone Res. 2026 May 28;14(1):59. doi: 10.1038/s41413-026-00544-2. PMID: 42209460; PMCID: PMC13219498.
New Publication in Nature Communications
Zhang M, Feng J, Guo T, Meng L, Pei F, Gao L, Yang Y, Ho TV, Chai Y. Canonical BAF chromatin remodeling complex specifies stem cell fate via cell-type-specific co-factor recruitment. Nat Commun. 2026 Mar 3;17(1):3361. doi: 10.1038/s41467-026-70038-6. PMID: 41771870; PMCID: PMC13066034.
New Publication in Proceedings of the National Academy of Sciences
Meng L, Feng J, Guo T, Zhang M, Cha S, Chen P, Ziaei H, Harouni A, Ho TV, Chai Y. Piezo2+ mechanosensory neurons orchestrate postnatal development through mechano-chemo-transduction of PDGFA signaling. Proc Natl Acad Sci U S A. 2025 Jul 15;122(28):e2504103122. doi: 10.1073/pnas.2504103122. Epub 2025 Jul 8. PMID: 40627386.
New Publication Accepted in The Journal of Bone and Mineral Research
Buchanan C, Chen S, Yuan Y, Guo T, Feng J, Zhang M, Carey G, Howard I, Sanchez J, Ho TV, Chai Y. Loss of Runx2 in Gli1+ Osteogenic Progenitors Prevents Bone Loss Following Ovariectomy. JBMR Plus, 2024; ziae141, https://doi.org/10.1093/jbmrpl/ziae141.
New Publication in Bone Research
Pei F, Guo T, Zhang M, Ma L, Jing J, Feng J, Ho T-V, Wen Q, Chai Y. FGF signaling modulates mechanotransduction/WNT signaling in progenitors during tooth root development. Bone Res 12, 37 (2024). https://doi.org/10.1038/s41413-024-00345-5.
New Publication in Nature Communications
Zhang M, Guo T, Pei F, Feng J, Jing J, Xu J, Yamada T, Ho T-V, Du J, Sehgal P, Chai Y. ARID1B maintains mesenchymal stem cell quiescence via inhibition of BCL11B-mediated non-canonical Activin signaling. Nat Commun 15, 4614 (2024). https://doi.org/10.1038/s41467-024-48285-2.
New Publication in Cell Stem Cell
Guo, T., Pei, F., Zhang, M., Yamada, T., Feng, J., Jing, J., Ho, T-V, and Chai, Y. Vascular architecture regulates mesenchymal stromal cell heterogeneity via p53-PDGF signaling in the mouse incisor. Cell Stem Cell. 2024 May 03. https://doi.org/10.1016/j.stem.2024.04.011.
New Publication in Plastic and Reconstructive Surgery
Stanton E, Feng J, Kondra K, Sanchez J, Jimenez C, Brown KS, Skiles ML, Urata MM, Chai Y, Hammoudeh JA. A Calvarial Defect Model to Investigate the Osteogenic Potential of Umbilical Cord Stem Cells in Bone Regeneration. Plast Reconstr Surg. 2024 Mar 1;153(3):637-646. doi: 10.1097/PRS.0000000000010754. Epub 2023 May 24. PMID: 37224290.